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Depression is an illness, not a state of mind or a weakness.
Depression is caused by a chemical imbalance in the brain, but there are also other factors that may play a role as well, such as:
environment - a significant loss, a difficult relationship or financial problems all produce stress. The body, by secreting extra amounts of certain hormones persisting for a long time, can produce changes in the brain actually killing some of the nerve cells.
psychological - peoples whose personalities involve pessimistic thinking, low self-esteem and excessive worrying are more likely to develop depression...
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