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Essay text:
The abnormal ovum or sperm is derived from a germ cell in
which the pair of 21st chromosomes holds together and passes into the same sperm
or ovum instead of separating. In the type of Down syndrome called
translocation, the extra chromosome 21 material is attached to one of the other
chromosomes; when some, but not all, of the body's cells carry an extra
chromosome 21, the condition is a type of Down syndrome called mosaicism.
Because of the extra chromosome 21, children with Down syndrome often
have some characteristic physical features, such as a small head, a flat face,
slightly upward slanted eyelids, skin folds at the inner corners of the eyes,
small nose and mouth, and small hands and feet...
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