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WNV is a spherical shaped particle approx 50 nm in diameter and consists of a lipid bilayer membrane that surrounds a nucleocapsid core containing a single stranded positive-sense RNA strand with approximately 12,000 nucleotides (1, 6). It is not a single virus but a series of closely related virus’s. There have been two distinct lineages of global WNV (I and II) isolated through the use of phylogenetic analysis. Lineage I is primarily related to outbreaks of the virus in humans, birds and horses. It can further be divided into three clades (1a, 1b and 1c). The different clades are responsible for different types of animal outbreaks in different areas...
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