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To avoid this the amino groups are converted into urea, which is less toxic and can be transported and stored to be released by the excretory system.
Urea is the result of two amino groups being joined to a carbonyl (C=O) to form CO(NH2)2, the process of which is called the ornithine cycle and takes place in the liver. The ornithine cycle was developed by Hans Krebs in 1932 and is similar to the Krebs cycle through the use of oxaloacetate. One of the steps in the cycle the breakdown of arginine into ornithine and urea, a reaction catalysed by the enzyme arginase. (See below)
(Fig 1.0)
Arginine Orthinine Urea
Urease is the enzyme which catalyses the hydrolysis of urea according to the following equation:
(NH2)2CO(aq) + 3H2O(l) ? CO2(g) + 2NH3(g)
The acidic ammonium carbonate is formed because the carbon dioxide dissolves in water to produce carbonic acid (H2CO3), which immediately reacts with ammonia to form the ammonium carbonate...
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