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D. Thromolytic agents are agents which dissolve blood clots. All thrombolytic agents act systematically and have the potential to lyse a fresh platelet-fibrin clot anywhere and cause bleeding at the site.. Their therapy is only recommended for patients with acute massive pulmonary embolism who are hemodynamically unstable and not prone to bleeding. Intracranial disease, recent surgery, trauma, and hemorrhagic disease are contraindicated to thrombolytic therapy. The approved thrombolytic agents to treat PE and venous thromboembolism are: urokinase, streptokinase, and recombinant tissue plasminogen activator (tPA)...
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