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Essay Details:
Essay text:
The pattern of fat
accretion in the whole carcass is first described to
emphasise that the marbling depot is relatively late
maturing. The pathways of fat metabolism are then
discussed with the aim of examining the possibility of
regulating fat partitioning between depots in ruminants.
The importance of acetate versus glucose + lactate as
substrates for lipogenesis differs between depots in
the ruminant and it is proposed that this might allow for
differential control of lipogenesis. The role of diet in the
manipulation of pathways for lipogenesis in ruminants
is then explored. Both glucose infusion and diets
promoting starch digestion in the small intestine
increase the activity of enzymes (ATP citrate lyase)
associated with lipogenesis from glucose indicating a
greater relative importance of glucose as a lipogenic
substrate and this may have an impact on the relative
growth of different fat depots via the glucose/insulin
axis...
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