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These metabolic changes are caused by release of stress hormones (catecholamine and epinephrine) by adrenal glands. When stressful situation goes away, body returns to its normal state. But if the stress is chronic, the mechanism remains activated and organism is exposed to the high level of hormones for the long periods of time. As a result, blood pressure and heart rate are constantly elevated, which can take a toll on the cardiovascular system and cause a serious heart disease and even a stroke. (1)
There are many studies on humans and animals that had shown detrimental affect of stress on the cardiovascular system...
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