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The Raphe Nuclei are found in the medulla, pons and midbrain which are all located at the top of the spinal cord. Serotonergic neurons have axons which project to many different parts of the brain, therefore serotonin affects (Rosling, Claire, 2004). In the body, serotonin is synthesized from the amino acid tryptophan by the activity of the enzymes Tryptophan hydroxylase (TPH) and Amino acid decarboxylase (DDC) (Dolnak, Douglas R. DO, 2006). The enzyme tryptophan hydroxylase adds a hydroxyl group to tryptophan's benzene ring at position 5, creating 5-hydroxytryptophan. Another enzyme, amino acid decarboxylase, then removes a carboxyl group from 5-hydroxytryptophan, forming 5-hydroxytryptamine which is more commonly known as serotonin...
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Common topics in this essay:
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