Pharma

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Title: Pharma

Essay Details:

Subject: Science

Author: Michael S

Date: November 1, 2015

Level: University

Grade: A

Length: 1 / 214

Essay text:

These drugs depress the central nervous system and produce unconsciousness or sleep. In this experiment, thiopentone and pentobarbitone were selected, as examples of ultra-short- and intermediate-acting barbiturates respectively, to illustrate their differences in duration of drug action. Thus, the “righting reflex” of mice, ability to turnover immediately when the mice were placed on their back, is used to assess whether or not they are “asleep”. The onset and duration of sleeping time are recorded in order to show the duration of drug actions. Moreover, barbiturates’ interactions with other drugs through either pharmacokinetic or pharmacodynamic mechanism will also be examined...

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