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These antibodies produce a reaction that leads to a separation of epidermal cells.
Pemphigus is a very rare disease an occurs almost exclusively in middle-age or older people. About half of the cases of pemphigus begin with blisters in the mouth then follow with skin blistering.
There are three categories of pemphigus: vulgaris, foliaceus, and paraneoplastic pemphigus.
Pemphigus Vulgaris (PV), is the most frequently diagnosed form of pemphigus. Sores and blisters almost always start in the mouth. It doesn't affect any of the internal organs because the blisters can go as far down as the vocal cords...
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