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(Structures located in the middle of the brain, which form the striatum, input station of the basal ganglia system.) Dopamine affects brain processes that control movement, emotional response, and ability to experience pleasure and pain. The main symptoms of Parkinson's are due to a deficiency in the production of the neurotransmitter dopamine.
When dopamine producing cells in the substantia nigra fail, the striatum becomes deficient in dopamine. This causes other parts of the basal ganglia to become unregulated, resulting in problems of physical control. Signs and symptoms of Parkinson's disease may include loss of automatic movements, impaired speech/balance, rigid muscles and tremors...
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