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Nondisjunction occurs when these chromosome fail to segregate and can cause common abnormality of having an extra chromosome or missing a chromosome in its cells thus creating an offspring with chromosome abnormalities of 45 or 47.
Chromosome is a structure located inside the nucleus (center) of a cell that has long DNA molecule and proteins that present in every cell of the body. It also carries portions of the hereditary information needed for that cell to develop. Homologous chromosomes are chromosomes that occur in pairs. Normal humans have twenty-three homologous pairs.
A female's egg contains only one representative from each of the 23 chromosome pairs and the male's sperm contains the other half of the 23 chromosome pairs...
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