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The protein, p53, helps protect against the development of cancer, however reducing it has been shown to extend lifespan in fruit flies by up to 58 percent.
Dr Helfand, along with postdoctoral research fellow Johannes Bauer and associates, studied batches of flies modified to have reduced p53 activity in various small areas of their nervous systems. In each group, the flies survived their average lifespan of approximately two months. However, when a cluster of fourteen insulin-producing cells in the brains of one group of flies were altered to have lower p53 activity, the flies lived 15 to 20 percent longer than average...
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