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In an autoimmune disease, the immune system makes antibodies against parts of one's own body tissues.
Muscles are stimulated to contract by the transmission of nerve impulses to the muscle fibers. The nerve impulses cause the presynaptic cell to release the neurotransmitter acetylcholine into the synaptic cleft. There it is picked up by the acetylcholine receptors of the postsynaptic cell on the muscle fiber. In return this causes the myosin and the actin to slide past each other and link. This causes the muscle to contract. In MG, the immune system sees the acetylcholine receptors as foreign and therefore produces antibodies to attack and destroy them...
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