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This rabbit experiment was responsible for a large portion of what scientists now know about myasthenia gravis.
Myasthenia gravis causes a progressive and abnormally rapid fatigue of the voluntary muscles. It is known as an autoimmune disease, in which the body generates an immune system attack against its own skeletal muscles. This arises when lymphocytes in the blood produce antibodies that destroy muscle-cell receptors for acetylcholine molecules, preventing muscle contractions. The antibodies have been shown to decrease the usefulness of acetylcholine receptors through accelerated endocytosis and blockade of the receptor...
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