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In BSE, the unknown agent causes the cow's brain cells to die, forming sponge-like holes in the brain. The cow behaves strangely and eventually dies. The connection between BSE and humans was uncovered in Great Britain in the 1990s when several young people died of a human brain disorder, a new variation of a rare brain disorder called Creutzfeldt-Jakob Disease (CJD), which typically strikes elderly people. The new variation is called new variant Creutzfeldt-Jakob Disease (nvCJD). Eating meat from cows that have been contaminated with Mad Cow Disease also exposed humans to the disease.
BSE is thought to have come from a similar disease in sheep called scrapie...
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