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The inner mitochondrial membrane of certain tissues contain a large amount of thermogenin (an uncoupling protein) which acts as an uncoupler by forming another pathway for the protons to flow down from the electron transport system back to matrix.
The Krebs cycle begins with the oxidation of pyruvate. This produces one CO2 and one acetyl-CoA. The Acetyl-coA reacts with oxaloacetate to form citrate. Citrate is converted back to oxaloacetate through a series of reactions. This produces 2 cO2 and uses 3 NAD+ and 3 H+. It consumes 3 H20 and one FAD, which produces FADH+. After the first turn, one ATP is produced as well as 3 NADH, 1 FADH2, and 2 CO2...
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