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Researchers analyzed patterns of T-cell responses caused by HSP60 in 57 patients with juvenile idiopathic arthritis while comparing them to controls.
Total test subjects numbered 104. Blood samples were taken from the 57 arthritics, 20 with juvenile onset diabetes, and 27 "healthy" children. Researchers used matrix based computer algorithms to select four pairs of potential HSP60 epitopes. Antigen specific activity of what researchers refer to as peripheral blood mononuclear cells, (PBMC) of these subjects were compared to samples from healthy controls for the purpose of observing T-cell responses...
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