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The process of MS occurs when the bodies T-cells antigen specific receptors bind onto the nervous system’s myelin, recognizing it as an antigen and thus initiating an immune response. (Compston et al, 2006). When activated, T-cells reproduce clones, which bear the same receptors specific for cells of the myelin sheath. Cytokines are released which adhere to the blood brain barrier (bbb), and thus thinning this barrier. Further attacks allow the T cells to cross the bbb which are usually prohibited from entering. (Minagar, 2003). The protein which make up the T cells bind onto the myelin fragments of the microglial cells causing a secondary activation, triggering further replication and the release of more cytokines...
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