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This is shown in figure 1 and results in a reduction of population fitness.
Figure 1 Adapted from Madsen (1996)
However the overdominance hypothesis suggests that because inbreeding increases homozygotes it reduces the overall frequency of the superior heterozygote's relative to Hardy Weinberg ratios if the population was randomly mating. This results in the loss of the heterozygote advantage and in a decrease in fitness (Charlesworth and Charlesworth 1987).
Both hypotheses are likely to be correct and that a combination of the two causes an overall increase in homozygotes and decrease in heterozygotes of the offspring relative to that of the population as a whole if it were mating randomly and in Hardy Weinberg frequencies...
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