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Both viruses establish latent infections in sensory neurons and, upon reactivation, cause lesions at or near point of entry into the body.
While HSV-1 and HSV-2 are different viruses, under a microscope, HSV-1 and 2 are virtually identical, sharing approximately 50% of their DNA and are treated similarly.
HSV-1 and HSV-2 contain a large double-stranded DNA molecule. HSV is gram negative, consists of 162 capsomers and replication takes place within the nuclei of eukaryotic cells. The HSV virion has four parts: an electrondense core containing viral DNA; an icosapentahedral capsid; a tegument-an amorphous layer of proteins that surround the capsid; and an envelope...
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