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The fundamental reasoning in these models is that deleterious mutations can build up in a lineage such that it decreases an organism’s overall fitness. Sex is then thought to be more efficient at removing deleterious mutations from the genome through recombination. An asexual lineage would have to rely on a reversal mutation to remove deleterious alleles. Two models in this subset are Muller’s ratchet hypothesis, and the deterministic mutation model, that I will discuss in more detail.
Muller’s ratchet hypothesis considers an asexual population to act as a ratchet. When mutations arise in the least mutated individuals in a population, further generations cannot have fewer mutations in that population, provided that back mutations don’t exist...
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