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1). This can extend around the entire circumference of the aorta or just effect a portion. "The gross pathology of coarctation varies considerably," (Shah, 2005, p. 1). The lesion can be long, segmental or tortuous. It is commonly found distal to the origin of the left subclavian artery (Shah, 2005, p. 1). The abnormality occurs in embryological development. Coarctation is do to an abnormality in the left fourth and sixth aortic arches that occurs at this stage. This anomaly "can be explained by 2 theories, the ductus tissue theory and the hemodynamic theory," (Shah, 2005, p. 2).
In the ductus tissue theory it is thought, "coarctation develops as the result of migration of ductus smooth muscle cells into the periductal aorta, with subsequent constriction and narrowing of the aortic lumen" (Shah, 2005, p...
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