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They might be born disabled. Disorders may show up later in their life. Such problems have been seen in other cloned mammals, such as reproductive problems. There is no reason to that this won't happen in a humans' case. Large scale cloning could eliminate genetic originality. It is diversity that causes evolution and adaptation. It prevents an entire species from disappearing because of a disease.
The people out there who are childless because of a rare hereditary disease would be able to produce offspring that were genetically theirs. However, if the cloned sheep "Dolly" were anything to go by then less than one in a hundred success rate would cause many problems...
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