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trachoma is the mucous membranes of the body found in the genital region, throat, and eyes.
?? The etiological agent of Chlamydia is C. trachomatis which has the following general characteristics:
obligate intracellular parasite
gram negative coccoid bacteria
nonmotile intracellular
does not possess a peptidoglycan layer
unable to produce its own ATP.
?? The following tests are used to identify C. trachomatis:
1) ELISA test and FA test may be effective only when the bacterium is metabolically active (not infectious), these tests are used to detect group specific LPS and strain-specific outer membrane proteins
2) gram staining (negative, coccoid)
3) culture and iodine staining for inclusion bodies (used because the trachoma species of Chlamydia cannot be stained with iodine because it does not contain glycogen)
4) Serological tests that detect high titer IgM antibodies indicates a recent infection (used in adults, cannot distinguish between current and previous infections, not very useful)
5) nucleic acid probes (these are currently new and further info was not available)
?? The bacterium C...
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