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If particles are small there is a larger surface area for the substance to react on thus increasing the probability of a collision, increasing the rate of reaction and decreasing the time of the reaction.
Small surface area large surface area
Another thing that affects the rate of reaction is the atomic structure of the chemical. If we are dealing with elements the electrons on the outer shell determine how well they react, e.g. if the outer shell is full of electrons like neon it has very little intentions to react, but if there is only one electron in the outer shell or seven these elements will be highly reactive...
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