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In many individuals, limbs are in a weakened state or even paralyzed, which leads to under development of muscles in those limbs. Spasticity is the term that refers to increased tone or tension in a muscle. Spacticity negatively affects muscles and joints of the extremities, causing irregular movements that are particularly harmful in growing children. The known adverse effects of spasticity include inhibition of movement, inhibition of longitudinal muscle growth, inhibition of protein synthesis in muscle cells, limited stretching of muscles in daily activities, development of muscle and joint deformities...
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