- Your research paper is written by certified writers
- Your requirements and targets are always met
- You are able to control the progress of your writing assignment
- You get a chance to become an excellent student!
Essay Details:
Essay text:
Revised November 14, 2005. Accepted November 14, 2005.
The trans-activation response (TAR) RNA stem–loop that occurs at the 5' end of HIV RNA transcripts is an important antiviral target and is the site of interaction of the HIV-1 Tat protein together with host cellular factors. Oligonucleotides and their analogues targeted to TAR are potential antiviral candidates. We have investigated a range of cell penetrating peptide (CPP) conjugates of a 16mer peptide nucleic acid (PNA) analogue targeted to the apical stem–loop of TAR and show that disulfide-linked PNA conjugates of two types of CPP (Transportan or a novel chimeric peptide R6-Penetratin) exhibit dose-dependent inhibition of Tat-dependent trans-activation in a HeLa cell assay when incubated for 24 h...
Showed 18% of text Buy database access to get full access to all 184 988 essays
Calculate a fair price for your order
Do you need an essay?
A professional team of writers is able to craft custom essays from scratch according to your instructions. We are ready to satisfy writing needs of every demanding customer.
Do you need many essays?
The product provided is intended to be used for research or study purposes. Get instant access to over 200,000 papers.
Common topics in this essay:
- Cell-Penetrating Peptide Conjugates Of Peptide Nucleic Acids (Pna) As Inhibitors Of Hiv-1 Tat-Dependent Trans-Activation In Cells
- Solid Phase Peptide Synthesis (SPPS)
- Nucleic Acids
- Stem Cells: The holy grail of medical research
- Biology Laboratory
- molecular biology review
- biology cells
- Evolution and Its Place In the Biology Classroom
- The Greatest Medical Breakthrough?the use of Pluripotent Stem Cells
- Cells And Cell Theory
- Biology Cell Parts
- Biology: cell functions
- Regulate Use of Cell Phones on the Road
- A Call to Action: Regulate Use of Cell Phones on the Road
- Stem Cell Technology:The Controversies surrounding Stem Cell Research
Feedback of people who used our services.
Similar Essays:
1 pages / 234 words |
|||
2 pages / 353 words |
|||
2 pages / 369 words |
|||
1 pages / 106 words |
|||
2 pages / 458 words |
|||
2 pages / 434 words |
|||
2 pages / 430 words |