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Essay text:
4
__ promoter site
__ repressor site
__ operator site
__ structural genes
__ inducer
Function Max. 4
__ binds RNA polymerase* at 3' site on DNA (* also cAMP-CAP)
__ produces repressor protein: stops RNA polymerase attaching to promoter
__ site of attachment of repressor protein
__ codes for sequential protein
__ serves to inactivate repressor
CONTROL OF mRNA PRODUCTION & CONSEQUENCES re PROTEIN SYNTHESIS:
__ Inducible model: derepression (lactose example) [gene always off] = 3 points
__ Repressible model: corepression (tryptophan-histidine) [gene always on]
= 3 points
__ CAP model: catabolite induction: with decrease in glucose -> increase in cAMP
cAMP-CAP binds to promoter site
therefore, transcription -> lactose metabolism = 3 points
(above require explanation & example)
__ Adaptive significance = 2 points
__ Final fate of mRNA transcribed = 2 points
Max...
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