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Enzymes are biochemical catalysts, which speed up reactions that would otherwise be too slow to be of any use to an organism. They control cell metabolism by regulating how and when reactions occur. Enzymes are globular proteins; they have complex structures in which the polypeptides of which they are composed show tertiary and often quaternary folding. The three dimensional shape of the protein is vital to its functioning. If altered, they will no longer be able to bind to the substrate (the molecule taking part in the reaction). Their shape is held in place by hydrogen bonds and ionic forces; these can be altered by changes in pH and temperature...
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