Ames Test

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Title: Ames Test

Essay Details:

Subject: Science

Author:

Date: February 16, 2016

Level: University

Grade: A

Length: 9 / 2486

Essay text:

typhimurium to wild-type.” (Ames et al., 1973 ; Maron and Ames, 1983; Hofnung and Qullardet, 1986) The trials that will be held in this lab will be tested under the Spot-Overlay Ames Test. It is a widely used technique for screening potential carcinogens by testing for mutagenesis of bacteria. It relies on the observation that the most common cause of cancer is somatic mutations brought about by DNA damage. It was first developed by Dr. Bruce Ames in 1971, and gave researchers a faster and less expensive way to get results. “This assay uses a set of histidine-requiring strains of the bacterium Salmonella typhimurium to detect mutations induced by a test agent...

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