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Normal cell function is disrupted by the virus in an infected cell and can trigger a process known as programmed cell death, or apoptosis. This is the body's attempt to rid itself of the infected cell.
Another mechanism that the HIV virus uses to destroy helper T-cells is direct cell killing. When an infected cell contains a large amount of the virus, the virus essentially "pops" the cell by attempting to bud through the cell membrane. Unfortunately, not only does the cells die, but it also releases more viruses into the body to infect other cells.
Lastly, HIV virus can also cause a helper T-cell to be unable to respond to immune system signals...
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