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What is a recommended 'steroid trial' for COPD?
A. The most frequently used regime for a steroid trial is to give oral prednisolone (40mg daily in a single morning dose) for 2 weeks. It is best to make measurements of peak expiratory flow (PEF) twice a day for 2 weeks before starting oral steroids in order to get a baseline value and then during the treatment period. FEV, should be measured at the beginning and end of the baseline period and after the inhaled steroids. A steroid trial is considered positive if FEV, or mean PEF increase by more than15%, when a diagnosis of asthma is made. It is important to remember that some patients will have asthma and COPD at
the same time...
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