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The findings were consistent in indicating an effect of paternal age, although it has been argued that selection bias was possible and that urban area controls could have been used (Bertranpetit & Fananas, 1993). Bertranpetit and Fananas (1993) matched for age, gender, place of birth, employment and neighborhood, but didn't find an association between schizophrenia and paternal age (Bertranpetit & Fananas, 1993).
This led to some speculation in the theory, but since then there have been a number of studies that have taken these variables into account and found an association. Although the age of risk varies slightly, they have large sample sizes and have adjusted for a number of different environmental variables...
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