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The presenile form was described more in detail by Alois Alzheimer as a progressive deterioration of intellect, memory and orientation. As a neuropathologist, Alzheimer studied the case a 51 year-old woman. When she died, Alzheimer performed an autopsy and found that she had "cerebral atrophy" (deterioration of the brain), "senile plaques" (protein deposits) and "neurofibrillary tangles" (abnormal filaments in nerve cells) in her brain -- three common pathological features of those who have Alzheimer's Disease.
Today, as research on Alzheimer's disease progresses, scientists are describing other abnormal anatomical and chemical changes associated with the disease...
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