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He also hypothesized that all substances and objects were made up of air, fire, water, and earth in different proportions. His proposal of the four humors of the body was later accepted by the Hippocratic school.
Each of Empedocles' four humors was connected to one of the four seasons. Black bile was considered to be a part of autumn, blood was associated with spring, phlegm with winter and summer with yellow bile. Each humor was identified with its corresponding season due to the belief that each humor contained certain qualities. These qualities were closely related to the conditions of the seasons...
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