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The problem has now reached widespread proportions. "Over the past three decades the vaccine infrastructure in the United States has steadily crumbled" (Serafini, 2006).
Supply
Since the 1950's, the supply of flu and childhood disease vaccines has continued to decrease due to financial reasons. Vaccine production hasn't traditionally been a lucrative business, and everything comes down to money (Serafini, 2006). It is not profitable enough for pharmaceutical companies to build expensive plants to supply the one or two doses needed for most vaccines when they can make more money manufacturing a drug that people will take daily for chronic conditions...
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