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This type of isolation is called geographical isolation. Their allele frequencies will change in different ways due to natural selection pressures. Sympatric speciation is the formation of a new species without geographical isolation. Strong forces of natural selection cause genetic differences between two populations that can in theory interbreed.
Natural selection can lead to a change in allele frequency. It is the process by which an environmental factor affects the survival rate of different phenotypes in a population. Selection can be stabilising, directional or disruptive. Stabilising selection takes place in a stable environment over time it usually favours ?average' members of a population...
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