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Because nerve cells that control muscular movement are not replaced once they are destroyed, poliovirus infection can cause permanent paralysis. When nerve cells in respiratory centers, which control breathing, are destroyed, the victim must be kept alive by an iron lung (see Artificial Respiration). For every paralytic case of poliomyelitis, however, there may be 100 nonparalytic cases.
Treatment
Because no drug developed so far has proved effective, treatment is entirely symptomatic. Use of moist heat coupled with physical therapy to stimulate the muscles was first initiated by the Australian nurse Elizabeth Kenny, and antispasmodic drugs are administered to produce muscular relaxation...
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