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The artery wall becomes thickened and looses its elasticity. (Fraser 2000)
The wall of an artery is composed of several layers. The lining or inner layer (endothelium) is usually smooth and unbroken. Atherosclerosis begins when the lining is injured or diseased. (Marieb 2006) Then certain white blood cells called monocytes are activated and move out of the bloodstream and through the lining of an artery into the artery's wall. Inside the lining, they are transformed into foam cells, which are cells that collect fatty materials, mainly cholesterol. (Clark 2007) In time, smooth muscle cells move from the middle layer into the lining of the artery's wall and multiply there...
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