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The genes of HIV-1 can be placed into 3 general categories: structural, regulatory, and accessory genes. The structural genes include gag, pol, and env. The regulatory genes include tat and rev. The accessory genes are nef, vpr, vpu, and vif (Vaccines 1999).
There are two major branches to the immune system in primates: a humoral or adaptive branch and a cell-mediated or innate branch. The cell-mediated immune response operates through MHC I via CD8+ (cytotoxic T cells). Antibodies are not secreted through this branch of the immune system, and the cell-mediated immune response generally targets viruses and other intracellular antigens...
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