Genetic Disorders

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Title: Genetic Disorders

Essay Details:

Subject: Miscellaneous

Author: David R

Date: December 28, 2015

Level: University

Grade: A

Length: 3 / 620

Essay text:

Death is the result of this disease, in children. With Tay-Sachs disease, the brain cells of a baby are unable to metabolize gangliosides, a type of lipid, because a crucial enzyme does not work properly. As the lipids accumulate in the brain, the brain cells gradually cease to function normally. Only children who inherit two copies of the Tay-Sachs allele qualifies as a recessive. At the biochemical level, we observe an intermediate phenotype characteristic of incomplete dominance: The enzyme deficiency that causes Tay Sachs disease can be detected in heterozygotes, who have an activity level of the lipid-metabolizing enzyme that is intermediate between individuals homozygous for the normal allele and individuals with Tay-Sachs disease...

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