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Chromosomes are individual, large DNA molecules in a cell nucleus. They contain the genes along with structures that hold the DNA and aid it in expressing heredity by orchestrating cellular operations.
Down syndrome is one of the most common chromosomal abnormalities, occurring in about 1 out of 800 births. However, the frequency of the disorder varies greatly according to the age of the mother. For women in their twenties the rate is 1 in 2,000 but it rises steeply to 1 in 100 by the time a woman reaches 40.
Down syndrome is usually recognized soon after birth because of characteristic facial features such as a flattened nose, upward slanting of the eyes, a large tongue that often protrudes from a small mouth, a small, rounded head, and a short stature...
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