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and functions of proteins are determained by genes problems with ion transport can be assumed to have a genetic basis. In 1989 an American Canadian research team found thre defect in the gene called the cystic fibrosis transmembrane conductance regulator gene ,produces a protein that usually helps maintain normal levels of chloride. In about 60% of cystic fibrosis pateints the protein made by the CFTR gene is missing an amino acid called phenylalanine
.When this amino acid is missing the protein doesn't
fold into its correct shape and loses its function. Researchers are not certain whether the defective protein is actually in tranport molecule...
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