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Although fat tissue produces estrogen, obese women tend to ovulate less frequently than leaner women, so they have less estrogen circulating in their bloodstream; such estrogen can fuel the growth of certain types of breast cancer.
In older women, however, fat tissue increases breast cancer risk because the estrogen from parts of the body other than the ovaries becomes more important. "Because postmenopausal women don't have estrogen produced in the ovaries, the vast majority of estrogen in these women is produced in the fat tissue," explains coauthor Heather Spencer Feigelson, PhD, a senior epidemiologist at the Atlanta-based American Cancer Society...
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