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Single-gene disorders are inherited in recognizable patterns: autosomal dominant, autosomal recessive, and X-linked.
Multifactorial inheritance -- Also called complex or polygenic inheritance. This type of inheritance is caused by a combination of environmental factors and mutations in multiple genes. For example, different genes that influence breast cancer susceptibility have been found on chromosomes 6, 11, 13, 14, 15, 17, and 22. Some common chronic diseases are multifactorial disorders.
Examples of multifactorial inheritance include heart disease, high blood pressure, Alzheimer's disease, arthritis, diabetes, cancer, and obesity...
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