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During the study, 58 women between ages 21 to 38 who had undergone surgery were broken up into two groups. One group was given 30 mg of pycnogenol twice a day for 48 weeks and the other group was given hormone treatments which were injection of leuprorelin. After four weeks into the study, the researchers notice that pycnogenol gradually reduced symptoms from severe to moderate. At the same time, the leuprorelin was more efficiently but after 24 weeks the treatment relapse and symptoms occurred again. The hormone treatment was discontinued because the leuprorelin was blocking estrogen in the body which was causing side effects...
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